Langues du site :

Partenaires

CNRS
UCBL
INRA
ENVL
FR41
IDEX




Rechercher

Sur ce site


Accueil > Pages Perso > Isaline Jacquemond

Equipe de Recherche Rhizosphère

Isaline Jacquemond

Doctorante

Activité

  • Thème de recherche :
    Influence du microbiote vaginal sur le développement du choc toxique staphylococcique d’origine menstruelle

Parcours scientifique

  • Licence Biologie, Biochimie, Chimie, Université Jean Monnet Saint-Etienne
  • Master 2 Recherche Ecologie microbienne, Université Claude Bernard Lyon1

Enseignement/Encadrement

  • 68h de travaux pratiques UE "Microorganismes et Fonctionnement des Ecosystèmes", Master "Ecosciences, Microbiologie", Université Claude Bernard Lyon1
  •  

Publications

2018



  • Jacquemond, I., Muggeo, A., Lamblin, G., Tristan, A., Gillet, Y., Bolze, P. A., et al. (2018). Complex ecological interactions of Staphylococcus aureus in tampons during menstruation. Scientific Reports, 8(1), 9942. doi:10.1038/s41598-018-28116-3
    Résumé : Menstrual toxic shock syndrome (mTSS) is a severe disease that occurs in healthy women vaginally colonized by Staphylococcus aureus producing toxic shock toxin 1 and who use tampons. The aim of the present study was to determine the impact of the composition of vaginal microbial communities on tampon colonisation by S. aureus during menses. We analysed the microbiota in menstrual fluids extracted from tampons from 108 healthy women and 7 mTSS cases. Using culture, S. aureus was detected in menstrual fluids of 40% of healthy volunteers and 100% of mTSS patients. Between class analysis of culturomic and 16S rRNA gene metabarcoding data indicated that the composition of the tampons’ microbiota differs according to the presence or absence of S. aureus and identify discriminating genera. However, the bacterial communities of tampon fluid positive for S. aureus did not cluster together. No difference in tampon microbiome richness, diversity, and ecological distance was observed between tampon vaginal fluids with or without S. aureus, and between healthy donors carrying S. aureus and mTSS patients. Our results show that the vagina is a major niche of. S. aureus in tampon users and the composition of the tampon microbiota control its virulence though more complex interactions than simple inhibition by lactic acid-producing bacterial species.
    Mots-clés : #3, #ibio.

Chapitre d’ouvrages

Vulgarisation

Communications Orales

Posters

2018

Article de revue


  • Jacquemond, I., Muggeo, A., Lamblin, G., Tristan, A., Gillet, Y., Bolze, P. A., et al. (2018). Complex ecological interactions of Staphylococcus aureus in tampons during menstruation. Scientific Reports, 8(1), 9942. doi:10.1038/s41598-018-28116-3
    Résumé : Menstrual toxic shock syndrome (mTSS) is a severe disease that occurs in healthy women vaginally colonized by Staphylococcus aureus producing toxic shock toxin 1 and who use tampons. The aim of the present study was to determine the impact of the composition of vaginal microbial communities on tampon colonisation by S. aureus during menses. We analysed the microbiota in menstrual fluids extracted from tampons from 108 healthy women and 7 mTSS cases. Using culture, S. aureus was detected in menstrual fluids of 40% of healthy volunteers and 100% of mTSS patients. Between class analysis of culturomic and 16S rRNA gene metabarcoding data indicated that the composition of the tampons’ microbiota differs according to the presence or absence of S. aureus and identify discriminating genera. However, the bacterial communities of tampon fluid positive for S. aureus did not cluster together. No difference in tampon microbiome richness, diversity, and ecological distance was observed between tampon vaginal fluids with or without S. aureus, and between healthy donors carrying S. aureus and mTSS patients. Our results show that the vagina is a major niche of. S. aureus in tampon users and the composition of the tampon microbiota control its virulence though more complex interactions than simple inhibition by lactic acid-producing bacterial species.
    Mots-clés : #3, #ibio.